There was an issue of the patcher failing to completely update for those who were trying to update from Patch 1 to Patch 3. This is fixed now but if you were affected by this and are now unable to run the game, you can fix it by downloading and installing the following patch over your existing installation. Sorry for the inconvenience.
http://downloads.hitechcreations.com/AH2200THRU2203.EXE