If your USB stick is sharing resources, by this I mean if you have 2 USB ports in front of the computer those 2 ports are connect to 1 USB ,for the lack of a better term, spot on the motherboard.
Warning, when you change your USB port for the stick you will have to recalibrate in windows and in the game and if you do not backup your settings folder you will need to remap your stick.
Update your sound and video drivers. If could be heat related, clean out the inside of the computer.
Not a lot of info to go on, so all these are just guesses