A few words about FNV mods.
A World of Pain adds significantly more places to FNV, more bad guys to shoot, several new vaults, caves, and perhaps more important, a couple of new sources of weapons and armor for the person starting a new game.
Portable tent is just what it sounds like, gives you a portable tent, fully loaded (or you can choose stripped down version) Can be equipped as a backback, setup wherever you like. (prefer to set mine close to water, lake mead, goodsprings source, etc) Inside you have a well rested bed, lots of storage, your own workbench and reloading bench. Tunable radio, and a plant box that lets you harvest food regularly.
Nocol (No collisions) This little mod takes the invisible walls out between the different area's.
I hated being told I can't go someplace.
If your not good at locks, I highly recomend the Classic Sonic Screwdriver.
Wasteland Essential Gear is a set of clothing and backpacks that you can either buy at good springs or find on some enemy body's. Varying from the +8 pounds small side pack to the big duffle bag.
They are extremely handy.
Tired of not being able to maintain a truly "neutral" character, or of being told your bad because your taking things that belonged to someone you just killed? Try the "Karma Neutralized" mod.
Like Fallout3, FNV has a world of interesting mods for the PC Gamer.
Your best one stop shop for mods is of course Fallout Nexus.
http://www.newvegasnexus.com/