Heard of it, the intern I used to work with had his desktop computer set to use Dvorak as the default, using a standard keyboard. No need to chop anything up. He didn't even move his keys around, because he was smart enough to know which key corresponded with which from qwerty to dvorak.
But if I for whatever reason need to log in on his computer, or log him off his account (I forget actually if it was tied to his account or his computer), it was a major major hassle to figure out how to type the administrator password.
My opinion is that it wasn't worth the hassle. My job has never required me to eek out a few more words per minute such that learning dvorak would be worth the effort.