Hey,
I use W7 64 bit, with SSD. No issues. No usb issues at all. Game crashes occassionally, very little actually, but its happens on log in. Just try again and fly. You will like the SSD, all tho it does not really affect game performance except for loading game. Put it in your port 0 sata port, install OS with only the SSD in. Add other drives only after you have put system in and its running. If you do a lot of editing on computer, add a spin drive to store all constant changing files. SSD's have a much shorter life span than spin drives, you'll want to limit writes to drive as much as possible. Do not do excessive benchmarks.
I would suggest the 64 bit OS, so you can use more than 3 GB's of ram.
I had a lot of problems with the SP1 update and IE9, currently not using them. Your copy might have that already in it. If not, Google it up before you try it. If the install develops issues, you do not just format and start again. SSD tech is way different than spin drives, maintenance is different. No defragging, no superfetch and some other things. Look into over provisioning and partition size before install of OS. W7 disk will handle the alignment of OS all on its own. Do some research to familarize yourself before install. Altho you may not be installing an OCZ SSD, they have a good forum with some quality info on SSD OS installs and maintenance. Also check for forum with your SSD manufacturer.
luck
ps: if you use an nForce chipset, leave SSD in IDE mode in bios. n Force had issues with SSD's. If Intel chipset, your gold, set bios for AHCI before OS install. Use latest bios version for mobo as well.