I always thought it would be cool for the automakers to come back out with classics except with modern drivetrains.
Sax, I don't know about the newest 5.0 but the 5.0 Windsor (302) they used until the fourth generation has been (relatively) unchanged over the years meaning it could be installed with a minimum of modifications. They continued to use the 302 in the explorers (and mountaineers) up until the 2002 model year so it's possible to get a relatively modern drivetrain implanted from one of those.
I have no experience with the '10/'11/'12 5.0 engine but I suspect it's completely different altogether.