Mossie buff turns better than you might think, but getting into a turning battle over enemy strats is not a healthy life choice. As you've noted though, it is the combination of speed, alt and timing theat work in the mossie's favour.
Plan your route ahead of time, try to be above 30k and going flat out (MIL, not WEP) by the time you get out on your own in a place where the red dar bar you generate in Badguyland will yell "strat raid" to any bad guy watching the map. Ditto for route out, I've had some success coming in, for example, to attack the knight city from the bishop side of the map, then high-tailing it back home to rook.
As the song says, you got to know when to hold 'em, know when to fold 'em. If there's a red dar bar over the strats you intend to attack for a while before you get there, you're likely going to be meat, so drop the idea and go bomb something less life-threatening. Same thing if you find yourself over a picket enemy cv group on your run in. I ignored the puffy one time because I was bored, my my weren't the skies over the city crowded and unfriendly.
Also, printing out the performance charts of the main interceptors can be a help - some bad guys have more / less of an advantage depending on alt. Don't want to go into a shallow dive if a gentle climb to 38k is your best option.
"Diving to ack / running to friends" is always OK too, you catch fewer channel 200 whines for doing it in an unarmed aircraft. Pays to note where the cvs are before you make your decision re: routes in and out.
Taking off with lots of fuel tends to give you more options - try to end up over BadGuyStrats with about 50% inners left, you can run forever on that, and you'll be free of drop tanks which slow you down a touch, not be too weighed down by internal fuel, and still likely have enough to get to safety if one or the other inner tank gets holed.
I don't recommend taking formations, too easy to lose too many perkies.