Theres not anything it really can't do. It can turn fight, E-fight, flat turn, loop, scissor. You name it, and the F4 can probably do it. The issue is, its not quite as maneuverable as the Spit V, so you'll be relying on the E-fighting aspects more than you typically would in the MA, where it can beat most of the planes you'll meet in a strait up knife fight, so keep that in mind. Its kind of hard to name any one thing that will help you out, since the F4 uses such a blend of techniques, but number one tip would likely be to turn if you see a possible shot.
For defense, scissoring works, although its not fantastic at it. Same goes for rolling defense, although they'll both be more effective against the Spit V, from what I remember of that particular model of Spitfire. Defensively, your man goal likely won't be to turn the tables on your opponent, since you can't really expect to do that against an equally skilled Spit V. Instead, you should focus on spoiling his gun solutions untill help can arrive.
Last-ditch, you can dive away, and try to seperate using your higher top speed. Remember, the F4 might not enjoy super high speeds, but neither do spitfires. They won't compress quite so fast, but they'll have heavy controlls, and be limited by black out to the same degree you are. And even if you don't escape, you will have equalized the energy states about as much as is possible, and put the fight back on something approaching an even keel.