The problem isn't catching bombers, really, but that bombers fly too fast in here. For ANY plane chasing them.
P.S. If you're of a mind to fire off your "BBs" to save weight and gain high alt performance, take the MG17 (7mm) option in the hangar. Why? Because those 7mm guns weigh a lot less than the 13mm guns, even after you drop the ammo. Some folks enjoy dumping the aft ammo, but I've had some on-again, off-again luck saving my butt by using them. I hesitate to dump them, but do on occasion. If you really want to save weight, mind the guns package you choose. The Mk103s are super effective, but heavier than the 4x20mm in total. Also, don't take WGrs... They're fun, but slow you down like a drag chute. You can load our Me410 out for high alt hunting, you just have to be careful about how you do it.