HiTech, I have direct experience in this area professionally (am a cofounder of one of the world's largest publicly traded patent-licensing companies, have managed IP legal teams and strategy, and have been involved in a number of patent fights related to being a cofounder of a couple of biotech companies -- patent wars are a standard part of the biotech business). There are ways that can potentially greatly minimize or eliminate such threats that are fairly quick and inexpensive to try. As a long-time AH enthusiast (and AW enthusiast before that), I'm happy to talk to you about it. My e-mail is brooke at customarrayinc.com -- if you want, just send me a an e-mail, and we can arrange a time to talk.