Sure you can, but it is inefficient.
What means efficiency exactly in this case? My point was, you don't have to avoid resupplying at at all when you want to get into the top 50. You can get there with, or without. A few runs here and there harldy have any impact on the overall rank. In fact, mine would not had been any better at all if I had refrained from resupply runs. And I would probably have to do scores of additional runs until there would be any change to the worse. (Maybe I will analyze this after conclusion of the current tour).
The 'efficiency' is more theoretical at this point. This only changes when you are specifically going for the #1 spot in vehicles or bombers. This really means you have to plan and put some restraints on your style of playing.
To get into
overall top 50, it's sufficient to be a good
complete player and doing about everything the MA offers, maybe doing the odd 'pro' score sortie here and there. No need to put too much restraints on your usual playstyle (which generally ain't much fun).
It's relatively easy to get a somewhat high overall rank, because most players couldn't care less about it and just concentrate on a few types of playing which are most fun to them.