Interesting indeed. While technology wise the F-22 is still superior in weapons and avionics, the Su-35 is still a big threat with their similar tech (abet if it's working) I don't think even a momentary skirmish the USAF or the Pentagon would be worried cause of three primary reasons
Firstly, what if the Russian's did shoot first, and shot down the F-22's or any other interceptor? So what?
Secondly, engagement doctrine is not built on moment-in-time scenarios, but long term strategy. So, sure, round 1 tactics may be a bit lame, but does it really matter for round 2 with gloves off?
And if they did shoot down or attempt to shoot down an intercepting force, would it matter what kind of aircraft are used? Could AI drones do the same job? (wouldn't that scare the sheit out of the ruskies?

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