Hiya,
Have you got a fan on your northbridge ?? (small chip near zif (socket/cpu))
Abits seem to clog-up with dust etc and after a while give a whining noise that usually dies off when fan warms up etc
If you have got a NB fan .... Power-off pc

And use a clean (preff new) small brush (paintbrush 1/2 -1in ideal) and clean fan etc
For a more longer lasting option if you are ok with it you can strip mobo out and remove NB hsf and clean fan etc better/more thoroughly, When cleaned apply some appropriate grease/spray to fan