Locking up things is one thing. Nothing you can reasonably do will make the house impregnable. The best defense is to make it look like there is someone there all the time. Make it look like it is not locked up and some one is home and the majority of burglars will pass it by. Not all of them just most of them. Doesn't mean you shouldn't lock the doors and windows. Have some timers to start things like the TV and or radio. Lights turning on and off at times will help out so that it looks like the place is occupied. Starting the garden sprinkler looks good too. If you can set the watering system, assuming you have one, to work during the hours you are working makes it look like you are taking care of the yard.