The more the world changes, the more things stay the same.
Bombers are dangerous when you rush to kill them. Such is the same in the real world, and it's why fighter escort worked. The fighter escort denied the attacking fighters the time to set up for good attacks on the bombers forcing them to either attack from directions the bombers were strong against, or to abort the attack. If you rush to attack the bombers you will lose. If you take the time to set up good high angle rate multi-axis change passes the bombers are easy meat. This is perhaps a bit of a problem in a game like ours where the durations involved are much shorter, but the essential survivability is similar.
HO's are a little bit different because the nature of the internet does give them a bit of an advantage if their gunnery is very good. But if you turn a little bit and use their commitment to an HO gun pass as an opportunity
to start a well timed lead-turn you can quickly turn the HO into a quick and consistent advantage for yourself. For the true HO-tard, they are an easy kill from that point on.
The most dangerous plane in the game is the one you assume is no threat.