If you include the Ariane, then you gotta mention the Proton. High reliability, low cost, mature design, the Proton has it all. It can carry more cargo to orbit then the Shuttle, costs a fraction of a shuttle launch, and has a good record going back almost 40 years. Gotta like it.
If you want to stick with US built stuff, stick around to see what happens with the EELV. It has the potential to offer lower costs per lb of heavy lift cargo to orbit, but as the Shuttle has shown, 'potential' doesn't mean 'guarentee'.
Take, for instance, the Titan IV. The Titan IV was built to carry shuttle designed payloads to polar orbits following the Air Forces withdrawal from the shuttle program following Challenger (and the sensible decision to take all the eggs out of the single national launching basket).
They took the mature Titan family design, which is a liquid fueled sustainer (as of the Titan IIIC, it had strapon solid boosters) and upgrade it to carry Hubble size spy satellites into orbit. Great plan, sounds like it should be cheap, right? Well...
I'm not sure how it happened, but development and contracts got a bit messed up. By the time it started launching (without blowing up, a significant milestone for the Titan IV and Ariane 5 for some reason), it was carrying cargo to orbit for MORE then the shuttle cost. That's right, the Titan IV will forever be known to many as the rocket that made the shuttle look economical.
Fast forward, the last Titan IV has been built. The US military has put their money behind a new generation launcher that should be able to lob all sizes of payloads for cheap. Two contractors are building them to foster competition so that prices will stay in control. So far, brilliant.
....then someone decides that if TWO companies are good, ONE company will be EVEN BETTER! So the market price controls have just gone out the window. Potentially, the EELV could be the cats pajamas for unmanned US defense launches and whatnot.
....but don't hold your breath.
Anyhow... the Proton has a colorful history. Yeah, a few have blown up over the last four decades, but for the cost, it's hard to beat. When launching unmanned cargo, Proton wins Chairboy's #1 Best Value Launcher(t) with a score of 4 Laika's.
BTW, the X-38 derived CRV program has been cancelled. More likely that the CEV will be used as a lifeboat, unless Kliper gets off the ground in Russia.