To set everything back to defaul, delete the settings folder in your AH game installment. It will recreate itself with default values on next startup of the game.
This will delete *all* custom settings for video, sound, radio, favorites, convergences, stick maps, keyboard maps etc.
Delete only the ####.kmp (keyboard map) and the stick.cfg in the settings folder to reset only JS and KB setup.
Edit: LoL TC, i admit quicktyping defeat to you

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