I've been doing a little more research, and have come up with the following #'s for a comparison. The 5" data I found on the sight I included above, and the 75mm info I got from Wikipedia. Can anyone verify that the numbers below are correct?
I know we don't have AP rounds in the game but I couldn't find the 75mm HE weight. This way it's an AP to AP comparison of relative force. The 5" HE weight is actually slightly higher at an even 25 Kg.
5" AP shell weight- 24.5 Kg
75mm AP shell weight- 6.32 Kg
5" average muzzle velocity (full charge) 762 m/s
75mm average muzzle velocity 619 m/s
given that F=MA (And if I can remember how to do this correctly

)
The 5" shell leaves the barrel at
19,354.8 Nm/s 
(25.4*762=19,354.8)
The 75mm shell leaves the barrel at
3,912.08 Nm/s (6.32*619=3,912.08)
It's just me, but if the target were 1,500 yards away, I'd want to be much further away from the 5" target.