I used to have some similar problem
This is a method I used to properly uninstall it:(from a diff forum)
The X52 pretty much runs up to the red line in terms of power draw available from USB which is why it's not recommended to run from a non self-powered hub - usually the USB ports on the backplane are the best.
If your PSU output is starting to decline (as they all do with age) it could possibly not be supplying enough power.
Alternatively you could try to roll back to when it was working before or you could try an uninstall/re-install.
if you've read
www.saitekforum.com then you should be familiar with
"First unplug your controllers, click Start>Run and type
ny -7 (drivers newer than 4.3.3.1727 )
(case sensitive) and click OK. Now go to Control Panel and run the Add/Remove Programs icon. Remove all Saitek entries in the list of programs and then go to the C:\Program Files directory and delete the Saitek folder. Restart your computer and the files will all be uninstalled.
Now browse to your C:\Windows\Inf folder (if you can't see an Inf folder then click Tools>Folder Options at the top of the window, then click View at the top of the window that comes up. In there click the dot next to the Show Hidden Files and Folders option and then click OK - you should now be able to find an Inf folder in the Windows directory) and look for the OEM0.inf file. Find the highest numbered OEMXX.inf file and double click on it - a Wordpad screen will open up with information in it. You're looking for any lines that refer to Saitek (usually at the top of the window). If you don't see any such info close that window and open the next OEMXX.inf file - so if you started on, say, OEM30.inf then you'd now open OEM29.inf.
If you find any that refer to us then close the window and delete that OEMXX.inf file along with its accompanying OEMXX.pnf file. Go through all of them until you have deleted any files that mention us.
Now do a search for files in Windows using the following search string:
sai*.*
Once it's finished finding any files delete them - files only though, don't delete any folders.
Now restart the PC and then install the X52"