Sure, if it is a strat such as HQ, I up at one of the bases near there (IF several raids have been made on it that night, or the same tard knocks it down a time or 2) I just try to position myself a couple of sectors in FRONT of his intended target. A lot of wash, rinse, repeat bombers have little imagination and typically fly the same plane, pattern, alt over and over and over. So guessing where they will come from isn't rocket science. (YES, I am guilty of this when I bomb too LOL)
When bases are being bombed all to hell from alt, watch the map. That map is mighty damn handy for knowing a lot of stuff. If bomber raids have been coming from a certain direction, look at the activity in that direction at more distant bases (if they are coming in at 15-20k or more) Chances are, you'll get an idea where they are lifting. I know that when I bomb, I try to find the highest alt base that is reasonably close enough to allow me to get to the alt I want and then allow my plane to reach top speed in time to calibrate the bomb site (oops forgot, you don't have to do that anymore). When you get an idea of where they are upping from, you can ambush them while they are grabbing alt... OFTEN bombers will go AFK until they feel like they have had enough climb time. When they are climbing, they are heavy and slow as crap... You can tear them up.... OR you can just fly cap a sector out from the area that is being hammered (TA152's will fly for ages at alt) You don't have to pee in the serial bomber's cheerios too many times before they move on to other targets.