If you mean to use it as a picker plane only, ....... LIES!!!!!!
It's an excellent dogfighter. Not a picking bird. You get in on a target, manuver for the kill, and kill the bastage in front of you!
The exception is of course when you're targetting a plane far more manuverable than yourself, such as a spitfire, zero, the 109s, etc.
The C205 is quite manuverable, but it suffers in turn radius. Somewhat like a 190, however, you can scrub off your surplus E in a turn to gain angles at the expense of position.
What I mean is the spitty might out turn you, but if you've got some speed or some alt to nose down, you can beat him on the break turn, or get your nose leading his enough to shoot him in his turn. Then break off, break high, reposition, and reattack. Don't play their game. This thing climbs like a 109f4/109g2.
Use the ammo load to set up lead shots. You can take the shots without fear of running out of ammo so fast. Also, get used to the views so that you know where an enemy is under your nose and so you can adjust your lead to better kill the targets.
Many planes are of comparable or worse turning radius than the C2. With these I never fear they will ever beat me, because I usually have better ability to regain or retain E (nice powerful engine on this puppy!). Against a P-51 or P-47 I have never really felt fear of losing a fight. Against 190s and other planes the risk is more "he'll just run away rather than fight."
I take these babies into fights all the time, and I love the guns, the overall flight capabilities the plane has. The major weakness is the lack of real range. You MUST cruise to and from the fight if you want a decent-length sortie. If it's a short hop such as base defense, or furballing less than 1 sector away, you can firewall the throttle or take 75% or less gas (if right over your field), but on any normal sortie I would say always take 100%. If we had DTs on this baby I'd fly it everywhere.
Fire all guns at once. You'll have a bit of surplus MG ammo once your cannons are gone, so you can use them for rangefinding as well as scaring other craft. They are, however, almost comparable to 50cal guns, and if you have to you can kill targets with just them (just get in under 300 yards -- under 200 is better).
It's not a GREAT plane. It's just good in a number of areas. Just barely fast enough to threaten most planes, climbs good but still can be outclimbed/zoomed by others, manuverability is good but still compresses horribly at higher speeds, so you can see it's not really a spit or la7 or 190d or anything.
Like the F6F, it is simply a good plane. I think you'll enjoy it.