To be honest I hate enemy fighters coming down dead 6 worse than ones who will set up the attack properly. Dead 6ers, particularly cannon birds, can put more heavier rounds on me from further out than the convergence of drone guns. Oh yes, I'll chew them up and the fight will be over in a couple seconds, but I usually end up loosing at least one drone. Wish I had the film, but one time I had a ta-152 dead 6 my b-17s and kill 2 drones with a couple hits each while I was steadily nailing him from 1k and then with all guns at D500.
I like having more ammo instead of the heavier hitting 50s. Tactics wont change in attacking lancs, I'll still dive down below and zoom up from underneath. What I have noticed is that the tail sight is a bit lower than the center of the screen. Switch back and forth between guns and you can see the difference.