I don't see why not... They had decent success during the last part of the war.
"The anti-aircraft version of the R4M used a large warhead of 55 mm. with 520 g. (17.6 ounces) of the strongly brisant Hexogen explosive charge, nearly guaranteeing a fighter kill with one hit, from the "shattering" force of its explosive warhead. Each R4M weighed 3.2 kg and was provided with enough fuel to be fired from 1000 m., outside the range of the bomber's defensive guns. The main body of the rocket consisted of a simple steel tube with eight base-hinged flip-out fins on the tail for stabilisation, deployed immediately after launch. A battery typically consisted of two groups of 12 rockets and when all 24 were salvoed in an attack, they would fill an area about 15 by 30 m. at 1000 m., a density that made it almost certain that the target would be hit."
"Though this tactic was effective, it came too late to have a real effect on the war, and only small numbers of Me 262s were equipped with the rocket packs. Most of those so equipped were Me 262A-1 (the one we have now), members of Jagdgeschwader 7. This method of attacking bombers became the standard, and mass deployment of Ruhrstahl X-4 guided missiles was cancelled."