We used to put 100LL in our cars in the old days for street racing and it helped out. was much cheaper than race fuel at the track. even with the additives for aircraft. we would run a richer mixture in the secondary side and also jet up a little on the primary's and pull up the timing. I know for a fact Octane does increase power. for naturally aspirated or blowers/superchargers.
you can see it in time slips at the drag strip. pump gas 93/94 octane will produce a couple 10th's lower ET ( even better with cold dense air) and MPH. hotter fuel+ more air = more torque and Horsepower.
you can tell the difference between 8 lbs of boost and 10 for sure.
then I went to nitrous uhhg.... everything comes down.... timing,shift points. the problem of stages and also the damage it does to motors when not tuned right. Valves/plugs/ lifting heads. the weather factors in big time. unless you very conservative.
also you are correct increasing the boost and raising over all compression would be redundant.( what was I thinking ) with the super charging. increasing the compression with the blower drive would give increase the power. dropping the compression and using variable supercharger gearing. the 51 has a 2 stage super charger so there are options with gearing.
as for turbos.... I am just starting to get involved in the turbos and there is is a lot of tun-ability in the modern turbos.. not so sure about the technology of what was available back then. I know I am planning on twins on my Challenger this year.

going for 1100 hp on 94 pump gas.
well.... the USA fuels were better quality overall and if we are going on the test numbers from US testing then I think the over all performance is askew a little. just my thoughts.
perhaps not a big difference but, maybe enough to count. I am sure that if we tested these aircraft the mechanics made sure they were well tuned.