The Glock is the first 'new' handgun design in many years with some good ideas and benefits. The quality of Glock's is very good as well. Most automatics other than Glocks are Browning designs or 'knock offs' of Browning designs. That is a real tribute to John Browning's genius, but not too innovative.
The combination of modern materials (plastics) which absorb some of the recoil energy combined with the spring loaded firing ping and pin blocking safety make for a highly effective and safe handgun. I have had no problems keeping a magazine of rounds inside a 3" diameter circle at 50 feet. A specialized load would probably enhance a Glock's accuracy if that's your goal. I would not consider Glock's exceptionally accurate but they are exceptionally reliable, safe, and easy to maintain.
For accuracy enhancements to the Ruger MKII, check out Brownell's parts and Volquartsen accessories. The Ruger .22 pistol is another very successful design which was not a direct Browning knock off.
Regards,
Malta