Yeah, there are a lot you don't want to disable... Some control internet connection, some control basic windows processes that you need, as important as "explorer" but named different things.
Here's what I did. I opened it up and went to the startup tab. I checked each and every entry. Look at where it is. "navapw32" is really norton antivirus. I leave that on. I disable it in my task bar if necessary. But I know it's norton because in the location field it lists the norton directory.
Some things I've looked up over time (google them) and for the most part it seems most are pretty necessary. ctfmon, wcesmon, etc... nvmctray is really nvidia's drivers (need this if you use any custom settings like color correction -- which I use for my partially burnt monitor). However nwiz you can safely disable if you don't use desktop profiles or anything.
Then there's the stuff I want running. MaxMem. Adobe gamma loader (a must), and zonealarm.
Anything blank uncheck. That's suspicious right there. If it's things you don't want loading uncheck it (i.e. roxio easy CD things, I don't want those running until I need to burn something).
So you have to consider each and every one. If you don't recognize it, don't mess with it. You might need it for basic windows functions.