I don't know about miswired, but homosexuals are certainly different in some way, and are certainly in the minority, so you could say they are abnormal. But we're talking about a relationship between two concenting adults. The only thing harmful in this are outside influences as far as I can tell. And if they do happen to be harming each other in some way in their concentual relationship, that's their business.
I'd have to believe (as I have no figures to back me up and am too lazy to try and search for it) that pedophiles are by far a smaller fraction of the population than homosexuals are. I've also read that children who are molested are quite a bit more likely to molest children when they reach adulthood. Whatever the case, pedophiles do serious harm to other individuals, and are not likely to be cured, so miswired brain or not, they should be put down. I'd feel just as comfortable with incurably phsychotic patients who are a threat to others being put down.
As to the religious view of homosexuality and other sinful ways in general, I just don't get it. "I don't hate you, but I love God, who will be sending you strait to hell when you die." That's just kinda hard for me to swallow. No explanation I've seen to this point has really gotten around that for me. And to stave off any heated rebuttles, I don't mean that as a judgement on anyone here...I don't know enough about any of you to make a sound judgement on your character. Well, except for Lazs...he's a big pansie.