My two all-purpose, light-weight, easy to shoot weapons are a Rossi SRS 92 (Winchester 1892 clone) chambered in .357 mag w/16" barrel and a Marlin Camp9 with six 20 round mags.
Both are outstanding "house" guns.
The Rossi 92 weighs 5.5 lb loaded, while the Marlin is about the same weight and size as the Ruger 10/22, but being chambered in 9mm, it offers decent knock down power (I load Winchester SilverTips or Remington Golden Sabre +P). Likewise, I prefer SilverTips in the Rossi as exposed lead HPs will distort when left in the tube mag for more than a few hours.
Both rifles are great for an afternoon of plinking.
My regards,
Widewing