The Beau would be mainly a scenario ride but anything with four Hizookas in the nose ought to see some use in the MA. However from a fighter standpoint it is hard to see why anyone would choose a Beaufighter over a Mosquito. It will be a fair bit slower and probably less maneuverable than the Mossie.
OTOH from a strike aircraft POV it ought to be a bit tougher than the Mossie and would have the option of carrying a torpedo and eight rockets. A Banff Strike Wing style mission with torpedo armed Beaus escorted by P-51s might be fun. The Beaus could come in high, drop some of the fleet's AA with rockets and then make their torp runs. It is never going to be as efficient in taking out a fleet in AH as using buffs, but a lot more realistic. Once the ord is gone the Beau would have a better chance vs fighters than any other torp armed aircraft.