There are a lot of differences in real life...
I wonder if the effects of explosive decompression will be modeled in game?
Also, they cruised to and from target at reduced throttle settings while engaged in combat. AH has full throttle. They took hours to climb to alt, in AH you'll be 30K inside 20-30 minutes. In real life they took 100% fuel (the max available allowed fuel for given bomb load, whatever your max T/O weight was, they flew at that), whereas in AH bombers are light, responsive, and nimble because they are flown at 25% almost always. In real life .50cal range, due to air buffet, gun vibration, and many other factors, was 500 yards max. In AH getting pinged accurately by .50cals is common place up to 1000 yards (or 1.5k if you're 30k alt, where the air is thinner and the rounds fly further).
So, it doesn't compare... What they went through was (yes I'll say it) easy compared to what we'll have to do to bring one of these babies down. Only difference is we get to do it more than once. Not a slight against Japanese pilots or anything, just saying the situations they faced as compared to how these will fly in AH's MAs are totally different.