Same experience here. The game runs fine with all the eye candy on, steady 60 FPS for like 20-30 minutes then it slowly decreases to 15-20. Alt+tabbing in and out usually solves this problem even though sometimes it causes game crashes. It can be annoying. Especially since this system runs everything else (mostly Napoleon Total War and Skyrim) very steadily.
Radeon HD-5830, the latest Catalist, PhenomII 955, 8GB Kingston DDR3-1600 ram, AH is on an OCZ Agility 3 SSD, 500W Chieftec PSU.