The ballistic trajectory profile is a result of the relationship between the round at initV in the chamber and it's travel down the barrel along with the barrel's relative relationship to gravity at the moment the round leaves the barrel. At an initial PSI that results in 500 M\sec at the exit of the 23 inch 30mm barrel with 1:16 twist. You have crappy dispersion that kills the round's effectiveness as a fighter to fighter gun in a single gun mounting. The added momentum from the plane's speed just means the round reaches it's crappy dispersion that much quicker. But, it is a negligible part of the overall components creating the trajectory profile. With a slow speed round with crappy ballistics, high aircraft speeds will tend to influence badly your ability to hit things unless you are traveling in a straight line.
Now if the velocity exiting the muzzle was 665 M\sec you would have a slightly better long range trajectory and dispersion past 100m. But, then you would have the recoil problems associated with the larger amount of propellant and probably a need for a slightly longer barrel. Then it would probably be too much for the small airframe of a 109 along with a weight increase overall of the gun so the action could survive the pounding. The original reason for the light weight low recoil of the Mk108 design with crappy ballistics. Or why you didn't see MK103 in gondolas mounted to 109's.
The MK108 ballistic profile in the game today, doesn't seem to be as friendly as it was 3 to 5 years ago. I no longer hear many players talking about making 400-600 yard kill shots as a standard with the tater anymore like they did back then. Players today seem to talk more about getting closer to achieve kill shots with the K4 and Ta152 against fighters.
Morph,
Mk103\Mk108 used the same round, different cases.
Mk103\108
Round\projectile = 3 cm M-Gesch. 108 Ausf.A m. Zerl.\3 cm M-Gesch. L.spur m. Zerl. / 3 cm M-Gesch. .Gl.spur m. Zerl.
Mk103 Case\Shell - 30x184B 860M\sec
Mk108 Case\Shell - 30×90RB 500M\sec