I've heard most of the damage from a nuke weapon is comparable to a meltdown, that is it goes straight down and is mainly used for hard underground targets such as bunkers. They must be on target. If this is the case, there should be modern weapons capable of doing the job without the radiation effect. There is no military purpose or rationale for their use other than for striking hard targets such as bunkers.
I would say "no" except for such a target that could not be disabled any other way. Sometimes targets such as this are located in a populated area. In this case another "no." One thing about using a nuke is it is a weapon of last resort, and is sure to open the door for retaliation in like manner. If our enemy uses it first, we should retaliate in like manner and to a degree fitting the situation. It basically boils down to the doctrine of MAD (mutually assured destruction.) This works as a deterrent because nobody wants the world to end this way. It works as defence only if it is not used, because once it starts, where will it stop?
I think it would be a bad idea to use it without a damn good reason to. If necessary, yes. If not, no.
Les
