Actually, safety in a pickup is misleading. By NTHSA records, you're 4 times more likely to be in a rollover accident in a truck/SUV than a passenger car or minivan. Surely there's peace of mind, but that doesn't equate to being safer.
On the other hand, in a pickup/SUV vs. passenger car accident, the car's passengers are 2 times as likely to suffer injuries than the passengers in the larger vehicle.
All in all, with the safety systems in late model vehicles, it's a toss up. If you can afford it and it makes you feel safer, so be it. I also see idiots in SUV's and trucks that think they're invincible that pay no mind to people in cars and on motorcycles. For instance, there's an obliviot (oblivious idiot) soccer mom type that barrels down my road every day in her suburban. Most of the time you see her, she's got her cellphone plastered to her ear, doing 50 in a 35. Is she safer than me in her urban assault Suburban? Possibly. Is she more of a danger to everyone else? Yes.
The knife cuts two ways gents.