I'm just speaking from my own experience here, but I don't think that any 190 will win any sort of "fight" against any P-38 (i.e. 190A-F, Ta-152, P-38G-L). The 190s in this game are kind of just lumbering dumptrucks, they used to be much more manueverable and dangerous (going back to AH1 days, anyway).
That said, the 190 is just manueverable enough that if you can catch the P-38 pilot off guard you can end a fight quickly, providing you hit the shot you get.
Co-E is the hardest fight for me if I'm in a 190. If I have an E advantage, I can generally manage to convert that to a killing shot. If I am at an E disadvantage, I can generally force an enemy pilot into bleeding off his excess energy trying to get a clean shot. Probably about 1/10 of the time, I get killed, 4/10 of the time the con blows his E, but stays fast enough to fly in front of me (and I hit the shot), and about half the time I miss the shot.
From there I can fight if I think the other guy is completely incompetent, or run if I think he has a quarter of a clue. Because co-E, no 190 has any shot at winning a fight against any model P-38 (or any model anything, really). Craptacular slow speed handling combined with atrocious turn performance pretty much guarantees that. The acceleration also really isn't anything to write home about.
Of course, in the MA the D-9 is used by folks who should really be in the La-7, but would never take advantage of the La-7s far superior manueverability (plus there is the stigma of using the "EZ MODE" plane). The D-9 is a good cherry picker, and as long as you keep it around 375 mph and fly in long straight lines, you will be able to maintain a decent K/D ratio.